Pneumococcal Septicaemia with Recovery

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Clinical burden of pneumococcal septicaemia

Background Streptococcus pneumoniae is a major cause of both mild and severe infections worldwide. The primary clinical syndromes associated with pneumococcal infections are pneumonia, meningitis, bloodstream infections and acute otitis media. Disease rates are highest in children <5 years of age, are low in older children and healthy young adults, and increase again in the elderly. The vast ma...

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A case of overwhelming pneumococcal septicaemia in a 34 year old man with coeliac disease and hyposplenism is reported. This previously unrecorded complication was fatal despite prompt treatment.

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Dramatic oligoclonal paraproteinaemia following a pneumococcal septicaemia.

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Postsplenectomy pneumococcal septicaemia resulting in gangrene of the extremities.

The enhanced susceptibility to certain infections following splenectomy has been increasingly recognised since the 1950's.' More recently the syndrome of overwhelming postsplenectomy infection (OPSI) has been defined.2 This describes the clinical picture of an acute fulminant illness, associated with disseminated intravascular coagulation and shock, progressing rapidly to coma and death within ...

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Systemic lupus erythematosus presenting as pneumococcal septicaemia and septic arthritis.

A 50 year old woman presented with pneumococcal septicaemia, septic arthritis, and a lobar pneumonia and was subsequently diagnosed as having systemic lupus erythematosus. The blood film and splenic 99mTc sulphur colloid uptake were normal, although selective functional hyposplenism was shown by the impaired clearance of immunoglobulin coated erythrocytes. Systemic lupus erythematosus presentin...

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ژورنال

عنوان ژورنال: BMJ

سال: 1941

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.4187.513